Preview the May 21 matchup between the Toronto Blue Jays and San Diego Padres with odds over/under, game spread, betting lines and more.

Its Wednesday, May 21 and the Padres (27-19) are in Toronto to take on the Blue Jays (23-24). Randy Vásquez is slated to take the mound for San Diego against Kevin Gausman for Toronto. The Padres are 4-6 in their last 10 games and third in the stacked NL West. After dropping game one of the series, the Padres have lost four straight games.

The Toronto Blue Jays got home runs from Vladimir Guerrero Jr. and Anthony Santander while Chris Bassitt threw six scoreless innings in a 3-0 win over the San Diego Padres last night.