After going through Afton in northeast Oklahoma, Route 66 heads straight across the state line to Neosho, Mo., where it turns north toward Joplin without going through Kansas at all.

Route 66 might be best known for its classic Americana, vintage motels, and endless roadside attractions—but these photos tell a deeper story. Photographer Anthony Presley captures the quieter ...

'Route 66: The Road and the Romance' at the Autry takes a national perspective on America's 'Main Street' with 250-plus artifacts.

Route 66 represents America’s adolescence, a time of exploring and trying new things and forming our personalities. Route 66 is where America learned to drive.

Route 66 has been called “the most famous highway in the world,” and it remains the ultimate road trip, as described in the new book, “Route 66 Still Kicks.” ...

Prairie grass sways in the wind. Route 66, commissioned in 1926 through the National Highway Act, is 75 years old this year. Tell it to the road. Officially, it is no longer a designated U.S. highway.

Our Route 66 road trip ended at the beginning, at East Jackson Boulevard and South Michigan Avenue in Chicago, where a brown sign hanging 12 feet high on a light post tells people they’ve ...

Oklahoma City is looking at creating a Route 66 landmark attraction that will celebrate the city's ties to the "Get your ...

Jim Ross and Shellee Graham are responsible for “Route 66: The First 100 Years,” a new book that takes readers on a journey through the historic highway's life, demise and renaissance.